A critical review on heat and mass transfer modelling of viral infection and virion evolution: The case of SARS-CoV2

Is it possible to characterize the SARS-CoV-2 viral infection by analyzing hijacking of cellular metabolism for its reproduction and multiplication? Gibbs free energy appears be critical factor successful virus infection. A always has a more negative growth than host. Hence, synthesis components is thermodynamically favourable. On other side, could essential better understand how S1 S2 spike protein interacts with ACE2 receptors cell membrane efficiently usual nutrients, which are intercepted. gives static model, does not include time arrow evolution. comprehension this evolutional path require an accurate analysis entropy generation or exergy disruption binding, replication, multiplication.